The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes.

Shea J AndrewsCaroline JonsonBrian Fulton-HowardAlan E RentonJennifer S YokoyamaKristine Yaffenull null

Published in: medRxiv : the preprint server for health sciences (2024)

We found that most participants in memory and aging clinics had at least one high-risk indicator for dementia. Furthermore, we observed a dose-response relationship where a greater number of risk indicators was associated with an increased risk of incident dementia.

Keyphrases

mild cognitive impairment
cognitive impairment
primary care
working memory
gene expression
metabolic syndrome
dna methylation
copy number
genome wide
glycemic control