Validation of ctDNA Quality Control Materials Through a Precompetitive Collaboration of the Foundation for the National Institutes of Health.
P Mickey WilliamsThomas ForbesSteven P LundKenneth D ColeHua-Jun HeChris KarlovichCloud P PaweletzDaniel StetsonLaura M YeeDana E ConnorsSusan M KeatingBenoit DestenavesMegan H ClevelandChristie J LauJ Carl BarrettGary J KelloffRobert T McCormackPublished in: JCO precision oncology (2021)
These results support the utility of the QCM in testing ctDNA assay analytical performance. However, unique designs and manufacturing methods for the QCM, and variations in a laboratory's testing configuration, may require testing of multiple QCMs to find the best reagents for accurate result interpretation.