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The small molecule BI-2852 induces a nonfunctional dimer of KRAS.

Timothy H TranPatrick AlexanderSrisathiyanarayanan DharmaiahConstance AgamasuDwight V NissleyFrank McCormickDominic EspositoDhirendra K SimanshuAndrew G StephenTrent E Balius
Published in: Proceedings of the National Academy of Sciences of the United States of America (2020)
Keyphrases
  • small molecule
  • protein protein
  • neuroendocrine tumors
  • wild type