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Metformin improves blood glucose by increasing incretins independent of changes in gluconeogenesis in youth with type 2 diabetes.

Celeste K L CravalhoAbby G MeyersLilian S MabundoAmber CourvilleShanna YangHongyi CaiYuhai DaiMary WalterPeter J WalterSusan SharmaShaji ChackoFran CogenSheela N MaggeMorey W HaymondStephanie T Chung
Published in: Diabetologia (2020)
Overall, the improved postprandial blood glucose levels and increase in incretins observed in the absence of changes in insulin sensitivity and gluconeogenesis, support an enteroinsular mechanistic pathway in youth with type 2 diabetes treated with short-term metformin.
Keyphrases
  • blood glucose
  • mental health
  • physical activity
  • glycemic control
  • young adults
  • blood pressure
  • type diabetes
  • newly diagnosed
  • insulin resistance