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Management and prognosis of patients with cancer of unknown primary: 20 years of experience.

Murat BardakçiEfnan AlginBüşra DüğeroğluÖznur BalFahriye Tuğba KöşDoğan Uncu
Published in: Turkish journal of medical sciences (2023)
CUP patients who receive multiple lines of chemotherapy tend to have longer survival. This is the first study to report cholestasis as a prognostic factor in CUP patients. In addition, the presence of lung metastases, not receiving second-line chemotherapy, and ECOG performance status (≥2) were found to be independent poor prognostic factors.
Keyphrases
  • prognostic factors
  • locally advanced
  • chemotherapy induced
  • rectal cancer
  • free survival