The effect of noise exposure on insulin sensitivity in mice may be mediated by the JNK/IRS1 pathway.

Lijie LiuCong FangJing YangHongyu ZhangYi HuangChuanying XuanYongfang WangShengwei LiJun ShaMingming ZhaMin Guo

Published in: Environmental health and preventive medicine (2018)

Impaired insulin sensitivity in noise-exposed mice might be mediated by an enhancement of the JNK/IRS1 pathway. Inflammation and oxidative stress might contribute to insulin resistance after chronic noise exposure.

Keyphrases

oxidative stress
high fat diet induced
insulin resistance
air pollution
induced apoptosis
signaling pathway
cell death
adipose tissue
type diabetes
dna damage
metabolic syndrome
high fat diet
ischemia reperfusion injury
skeletal muscle
wild type
endoplasmic reticulum stress
heat shock