Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection.
Zahra BahariZohreh JangraviHassan GhoshooniMohammad Reza AfarineshGholam Hossein MeftahiPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2021)
It is suggested that immunosuppressants, such as anti-rheumatoid drugs, could be considered as a potential approach for the treatment of cytokine storm in severe cases of COVID-19. One possible limitation of immunosuppressant therapy is their inhibitory effects on host anti-viral immune response. So, the appropriate timing of administration should be carefully considered.