Chronic treatment with zoledronic acid increases inflammatory markers in periodontium of rats.

Paulo Goberlânio de Barros SilvaAntonio Ernando Carlos Ferreira JuniorCamila Carvalho de OliveiraLuiz André Cavalcante BrizenoDeysi Viviana Tenazoa WongRoberto César Pereira Lima JúniorFabrício Bitú SousaMário Rogério Lima MotaAna Paula Negreiros Nunes Alves

Published in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2017)

Chronic treatment with ZA increase proinflammatory cytokines and the number of inflammatory cells in periodontium of rats and GSH are expressed probably in a compensatory manner.

Keyphrases

induced apoptosis
oxidative stress
signaling pathway
replacement therapy