Diagnostic fragmentation filtering for the discovery of new chaetoglobosins and cytochalasins.

Jacob P WalshJustin B RenaudShawn HoogstraDavid R McMullinAshraf IbrahimCobus M VisagieJoey B TanneyKen K-C YeungMark W Sumarah

Published in: Rapid communications in mass spectrometry : RCM (2019)

DFF is an effective LC/MS data analysis approach for rapidly identifying entire classes of compounds from complex mixtures. DFF has proved useful in the identification of new natural products and allowing for their partial characterization without the need for isolation.

Keyphrases

data analysis
small molecule
ionic liquid
high throughput
bioinformatics analysis