Spray-dried plasma deficient in high-molecular-weight multimers of von Willebrand factor retains hemostatic properties.
Michael Adam MeledeoQiyong Peter LiuGrantham C PeltierRyan C CarneyColby S McIntoshAshley S TaylorJames A BynumAnthony E PusateriAndrew P CapPublished in: Transfusion (2018)
Comparable coagulability was observed in FFP and SpDP. The apparent paradox between vWF-ristocetin cofactor assay and vWF-mediated platelet adhesion may be explained by the increase in smaller multimers of vWF in SpDP, producing different outcomes in these assays.