Pharmacokinetics of Tranexamic Acid (TXA) Delivered by Expeditious Routes in a Swine Model of Polytrauma and Hemorrhagic Shock.

Mallori WilsonSean StuartBrittany LassiterTimothy ParkerClyde MartinRobert HealyChristopher TreagerEric SulavaLorie GowerPravina FernandezEmily E Friedrich

Published in: Prehospital emergency care (2024)

all three methods reached the level needed to cause substantial inhibition of fibrinolysis within 10 min. The IV push method showed similar pharmacokinetics to IV infusion of TXA but can be delivered quickly without sacrificing an access site for 10 min.

Keyphrases

low dose