Hepatitis C virus genotyping based on Core and NS5B regions in Cameroonian patients.

Paul Alain Tagnouokam-NgoupoMarie Nicole NgoufackSebastien KenmoeSimon Frédéric LissockMarie Amougou-AtsamaRobert BanaiLaure NgonoRichard Njouom

Published in: Virology journal (2019)

We found high amplification rates of HCV in both core and NS5B regions, and a good concordance was obtained at genotype level using both regions except for two samples where putative 1-4 recombinants/multiple infections were detected. Therefore, HCV genotyping based on at least two genomic regions could help to identify putative recombinants and improve therapeutic management of HCV infection.

Keyphrases

hepatitis c virus
human immunodeficiency virus
end stage renal disease
high throughput
chronic kidney disease
genome wide
newly diagnosed
dengue virus
prognostic factors
gene expression
copy number
patient reported outcomes
dna methylation
zika virus
single cell
antiretroviral therapy