A genetic variant of pri-miR-182 may impact the risk for the onset of multiple sclerosis in the Iranian population.

Published in: American journal of human biology : the official journal of the Human Biology Council (2020)

Our findings illustrated that the pri-miR-182 rs4541843 G>A polymorphism is associated with the risk of MS in Isfahan population. However, additional large-scale association studies in various ethnicities and more molecular studies are necessary to elaborate our findings.

Keyphrases

multiple sclerosis
cell proliferation
long non coding rna
long noncoding rna
case control
mass spectrometry
white matter
copy number
gene expression
single molecule