DNA methylation alterations in the genome of a toddler with cri-du-chat syndrome.

Oxana Yu NaumovaSergey Y RychkovTatyana V KuznetzovaVeronika V OdintsovaSergey A Kornilov Elena L Grigorenko

Published in: Clinical case reports (2017)

This manuscript reports on genomewide epigenetic alterations in cri-du-chat syndrome related to a partial aneusomy of chromosome 5. A systematic analysis of these alterations will open up new possibilities for the prognostic evaluation of CDCS patients and the development of new therapeutic interventions for reducing the severity of the disease.

Keyphrases

dna methylation
end stage renal disease
gene expression
genome wide
ejection fraction
newly diagnosed
chronic kidney disease
minimally invasive
physical activity
peritoneal dialysis
copy number
prognostic factors
emergency department
patient reported