Dynamics of the alkyne → copper(I) interaction and its use in a heteroleptic four-component catalytic rotor.

Suchismita SahaSohom KunduPronay Kumar BiswasMichael Bolte Michael Schmittel

Published in: Chemical communications (Cambridge, England) (2022)

The HETPYNE (HETeroleptic Phenanthroline and alkYNE metal) and DABCO·(zinc porphyrin) 2 interactions were used to assemble the four-component nanorotor ROT-1 that exhibited a highly dynamic alkyne → copper(I) dissociation ( k 298 = 240 kHz) at 298 K. Quantitative click reaction transformed ROT-1 into the new rotor ROT-2 ( k 298 = 77 kHz) with a triazole → copper(I) linkage thus opening perspectives for bioorthogonal click strategies to biohybrid machinery.

Keyphrases

oxide nanoparticles
high frequency
electron transfer
photodynamic therapy
gene expression