Causal relationship between gut microbiota, plasma metabolites, inflammatory cytokines and abdominal aortic aneurysm: a Mendelian randomization study.
Chaozhong LiZhengqing LiuSiqian YangWanrong LiBo LiangHaoyu ChenYujia YeFang WangXiaoqing LiuYongliang JiangHaiying WuYunzhu PengZhaohui MengPublished in: Clinical and experimental hypertension (New York, N.Y. : 1993) (2024)
MR analysis has delineated a causal pathway from gut microbiota, through plasma circulating metabolites and inflammatory cytokines, to the pathogenesis of AAA. The role of intestinal flora and certain biomarkers may provide a reference for the diagnosis of AAA, and contribute to the prevention, diagnosis, and treatment of AAA disease.