Successful direct-acting antiviral therapy improves circulating mucosal-associated invariant T cells in patients with chronic HCV infection.

Apichaya KhlaiphuengsinNatthaya ChuaypenPimpayao SodsaiRangsima ReantragoonWin Min HanAnchalee AvihingsanonPisit Tangkijvanich

Published in: PloS one (2020)

These data indicated that dysregulation of MAIT cells might play a role in the progression of chronic HCV infection. Partial restoration of MAIT cell frequency and function was observed after successful DAA therapy, particularly in HCV-monoinfected patients.

Keyphrases

hepatitis c virus
end stage renal disease
induced apoptosis
newly diagnosed
chronic kidney disease
human immunodeficiency virus
ejection fraction
cell therapy
single cell
stem cells
machine learning
oxidative stress
patient reported outcomes
artificial intelligence