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The effects of epigenetic modifications on bone remodeling in age-related osteoporosis.

Wenyue YuHe-Ling WangJian-Ying ZhangChengcheng Yin
Published in: Connective tissue research (2022)
In this review, we summarized the epigenetic modifications of different bone-related cells during the development and progression of osteoporosis associated with aging. Additionally, we described a compensatory recovery mechanism under epigenetic regulation that may lead to new strategies for regulating bone remodeling in age-related osteoporosis.
Keyphrases
  • bone mineral density
  • postmenopausal women
  • body composition
  • dna methylation
  • gene expression
  • induced apoptosis
  • soft tissue
  • bone loss
  • cell proliferation
  • signaling pathway