Potential of ultra-highly sensitive immunoassays for hepatitis B surface and core-related antigens in patients with or without development of hepatocellular carcinoma after hepatitis B surface antigen seroclearance.

Fumitaka SuzukiTetsuya HosakaMasayasu ImaizumiMariko KobayashiChiharu OhueYoshiyuki SuzukiShunichiro FujiyamaYusuke KawamuraHitomi SezakiNorio AkutaMasahiro KobayashiSatoshi SaitohYasuji AraseKenji IkedaHiromitsu Kumada

Published in: Hepatology research : the official journal of the Japan Society of Hepatology (2021)

Residual low viral antigen might predict HCC development even if HBsAg seroclearance was achieved according to a conventional assay. The results suggest that iTACT assays of HBsAg and HBcrAg would be useful for monitoring CHB patients.

Keyphrases

hepatitis b virus
end stage renal disease
high throughput
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
high resolution
dendritic cells
mass spectrometry
fluorescent probe
molecularly imprinted
label free