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Upregulation of the CD155-CD226 Axis Is Associated With Muscle Inflammation and Disease Severity in Idiopathic Inflammatory Myopathies.

Wenli LiChuiwen DengHanbo YangXiaolan TianLida ChenQingyan LiuChang GaoXin LuGuo-Chun WangQing-Lin Peng
Published in: Neurology(R) neuroimmunology & neuroinflammation (2023)
These findings demonstrate that the CD155-CD226 axis is highly activated in inflamed muscle tissues of patients with IIM and is associated with muscle disease severity. Our data uncover the immunopathogenic role of the axis in the pathology of IIMs.
Keyphrases
  • skeletal muscle
  • oxidative stress
  • gene expression
  • cell proliferation
  • electronic health record
  • signaling pathway
  • big data
  • artificial intelligence
  • long non coding rna
  • data analysis