Shared genetic etiology between anxiety disorders and psychiatric and related intermediate phenotypes.

Kazutaka OhiTakeshi OtowaMihoko ShimadaTsukasa SasakiHisashi Tanii

Published in: Psychological medicine (2019)

Our findings suggest that common genetic variants underlying the risk of anxiety disorders contribute to elevated risks of MDD, SCZ, ADHD and neuroticism and reduced quality of life, putamen volume and cognitive performance. We suggest that the comorbidity of anxiety disorders is partly explained by common genetic variants.

Keyphrases

attention deficit hyperactivity disorder
major depressive disorder
mental health
autism spectrum disorder
working memory
genome wide
human health
copy number
risk assessment
bipolar disorder