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Molecular and Electrophysiological Characterization of Dorsal Horn Neurons in a GlyT2-iCre-tdTomato Mouse Line.

Xiaolan HePeng LiuXiao ZhangZhenhua JiangNan GuQun WangYan Lu
Published in: Journal of pain research (2021)
The present study indicated that spinal GlyT2-positive glycinergic neurons mainly received primary afferent Aβ fiber inputs; the GlyT2-P2A-iCre and GlyT2-tdTomato mice provided a useful animal model to further investigate the function of the GlyT2+-PKCγ+ feedforward inhibitory circuit in both physiological and pathological conditions.
Keyphrases
  • spinal cord
  • neuropathic pain
  • spinal cord injury
  • insulin resistance
  • protein kinase
  • wild type