A Network Pharmacology to Explore the Mechanism of Calculus Bovis in the Treatment of Ischemic Stroke.

Fangchen Liu Ling Li Jian Chen Ying Wu Yong-Bing Cao Ping Zhong

Published in: BioMed research international (2021)

Calculus Bovis may play a role in ischemic stroke by activating PI3K-AKT and MAPK signaling pathways, which are involved in regulating inflammatory response, cell apoptosis, and proliferation.

Keyphrases

signaling pathway
pi k akt
inflammatory response
cell proliferation
induced apoptosis
cell cycle arrest
epithelial mesenchymal transition
atrial fibrillation
lipopolysaccharide induced
toll like receptor
oxidative stress
immune response