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Activity of phytochemical constituents of Curcuma longa (turmeric) and Andrographis paniculata against coronavirus (COVID-19): an in silico approach.

Kalirajan RajagopalPotlapati VarakumarAparma BaliwadaGowramma Byran
Published in: Future journal of pharmaceutical sciences (2020)
Based on in silico investigations, the chemical constituents from turmeric like cyclocurcumin and curcumin and from Andrographis paniculata like andrographolide and dihydroxy dimethoxy flavone, significantly binding with the active site of SARS CoV-2 main protease, may produce significant activity and be useful for further development.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • molecular docking
  • coronavirus disease
  • transcription factor