Transcriptome Changes and Metabolic Outcomes After Bariatric Surgery in Adults With Obesity and Type 2 Diabetes.
Mamoon RashidAli Al QarniSaeed Al MahriSameer MohammadAltaf KhanMashan L AbdullahCynthia LeheReem Al AmoudiOmar S AldibasiAbderrezak BouchamaPublished in: Journal of the Endocrine Society (2023)
The changes in the transcriptome after bariatric surgery distinguish patients in whom diabetes enters complete remission from those who do not. The baseline transcriptome can contribute to the prediction of bariatric surgery-induced diabetes remission preoperatively.
Keyphrases
- type diabetes
- glycemic control
- bariatric surgery
- rna seq
- cardiovascular disease
- single cell
- weight loss
- genome wide
- gene expression
- end stage renal disease
- insulin resistance
- ejection fraction
- metabolic syndrome
- newly diagnosed
- chronic kidney disease
- disease activity
- high glucose
- ulcerative colitis
- diabetic rats
- patient reported outcomes
- oxidative stress
- drug induced
- adipose tissue
- systemic lupus erythematosus
- body mass index