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Subclonal Cancer Driver Mutations Are Prevalent in the Unresected Peritumoral Edema of Adult Diffuse Gliomas.

Hunter R UnderhillMichael J KarsyChristian J DavidsonSabine HellwigSamuel StevensonEric A GooldSydney VincentiDrew L SellersCharlie DeanBrion E HarrisonMary P BronnerHoward ColmanRandy L Jensen
Published in: Cancer research (2024)
True2 is a next-generation sequencing workflow that facilitates unbiased discovery of somatic mutations across the full range of variant allele frequencies, which could help identify residual disease vulnerabilities for targeted adjuvant therapies.
Keyphrases
  • copy number
  • papillary thyroid
  • high grade
  • small molecule
  • childhood cancer
  • early stage
  • low grade
  • squamous cell
  • cancer therapy
  • squamous cell carcinoma
  • lymph node metastasis
  • gene expression
  • dna methylation