Early-onset dementia and risk of hip fracture and major osteoporotic fractures.
Shoya MatsumotoTatsuya HosoiMitsutaka YakabeKenji FujimoriJunko TamakiShinichi NakatohShigeyuki IshiiNobukazu OkimotoMasahiro AkishitaMasayuki IkiSumito OgawaPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2024)
It is unknown whether early-onset dementia (EOD) increases the risk of fractures. We identified 13,614 individuals with EOD using a nationwide administrative database. Patients with EOD have a higher risk of hip, vertebral, and major osteoporotic fractures. The use of cholinesterase inhibitors may reduce hip fracture among patients with EOD.