The possible mechanism of Hippophae fructus oil applied in tympanic membrane repair identified based on network pharmacology and molecular docking.

Juntao HuangBing Mei TehZiqian XuZhechen YuanChong-Chang ZhouYunbin ShiYi Shen

Published in: Journal of clinical laboratory analysis (2021)

According to the analysis, HFO can be utilized to repair perforations by influencing cellular oxidative stress. Quercetin is one of the active compounds that potentially plays an important role in TM regeneration by influencing 17 gene proteins.

Keyphrases

molecular docking
oxidative stress
molecular dynamics simulations
stem cells
copy number
genome wide
ischemia reperfusion injury
induced apoptosis
wound healing