Autoimmune disease mouse model exhibits pulmonary arterial hypertension.

Koichi SugimotoKazuhiko NakazatoAkihiko SatoSatoshi SuzukiAkiomi YoshihisaTakeshi MachidaShu-Ichi SaitohHideharu SekineYasuchika Takeishi

Published in: PloS one (2017)

We showed that MRL/lpr mice were complicated with pulmonary hypertension. MRL/lpr mice appeared to be a useful model for studying the mechanism of pulmonary hypertension associated with connective tissue diseases.

Keyphrases

pulmonary hypertension
pulmonary arterial hypertension
pulmonary artery
mouse model
high fat diet induced
multiple sclerosis
coronary artery
type diabetes
metabolic syndrome
insulin resistance