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The inflammatory signature in monocytes of Sjögren's syndrome and systemic lupus erythematosus, revealed by the integrated Reactome and drug target analysis.

Kyung Eun LeeSeyoung MunSong-Mi KimWonseok ShinWon JungJoon PaekJungnam LeeErin HudsonWesley H ReevesKyudong HanSeunghee Cha
Published in: Genes & genomics (2022)
Taken together, our analysis indicates distinct inflammatory transcriptomic profiles shared in SjS and SLE monocytes. Comprehensive characterizations of the data from these conditions will ultimately allow differential diagnosis of each condition and identification of therapeutic targets.
Keyphrases
  • systemic lupus erythematosus
  • disease activity
  • oxidative stress
  • dendritic cells
  • emergency department
  • case report
  • drug induced