Helicobacter pylori eradication therapy outcome according to clarithromycin susceptibility testing in Japan.
Ryusuke HorieOsamu HandaTakashi AndoTakuya OseTakaaki MurakamiNorihisa SuzukiRei SendoEiko ImamotoYoshito ItohPublished in: Helicobacter (2020)
Clarithromycin-containing triple therapy even using vonoprazan did not achieve satisfactory eradication rates even in the clarithromycin-sensitive group. To avoid antibiotic misuse in population with low metronidazole resistance, 7-day vonoprazan, amoxicillin, and metronidazole triple therapy might be a strong candidate as a first-line eradication therapy.