CYP3A4*22 and CYP3A5*3 impact efficacy and safety of diazepam in patients with alcohol withdrawal syndrome.
Valentin Yurievich SkryabinJohan FranckVolker Martin LauschkeMikhail Sergeevich ZastrozhinValery Valerievich ShipitsynEvgeny Alekseevich BryunDmitry Alekseevich SychevPublished in: Nordic journal of psychiatry (2022)
These results suggest that genotyping for common CYP3A variants might have the potential to guide benzodiazepine withdrawal treatment.