Central generators of migraine and autonomic cephalalgias as targets for personalized pain management: Translational links.

Published in: European journal of pain (London, England) (2023)

This review focuses on the most relevant back and forward translational studies showing the crucial role of top-down brain modulation in triggering and maintaining primary headache states and how these central dysfunctions may interact with personalized pain management strategies.

Keyphrases

pain management
chronic pain
heart rate variability
resting state
white matter
functional connectivity
case control
multiple sclerosis
cerebral ischemia