Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice.
Kelsey S HideshimaAshkhan HojatiJustin M SaundersDoan M OnMario de la Fuente RevengaJong M ShinAna Sánchez-GonzálezCassandra M DunnAlexander B PaisAnthony C PaisMichael F MilesJennifer T WolstenholmeJavier González-MaesoPublished in: Psychopharmacology (2018)
These findings further support the existence of a functionally relevant crosstalk between 5-HT2A and mGlu2 receptors in different preclinical models of antipsychotic activity.