Extracorporeal Shockwave Therapy Alleviates Inflammatory Pain by Down-Regulating NLRP3 Inflammasome in Experimental Chronic Prostatitis and Chronic Pelvic Pain Syndrome.
Woong Jin BaeDongho ShinJun Jie PiaoSoomin KimYong Sun ChoiBong Hee ParkHyun Jin JungSamuel Ryan SorkhiSaager ChawlaChung Woon CheonDae Up KangJong Tae ChoiSang-Hyuck ParkSae Woong KimMahadevan Raj RajasekaranPublished in: The world journal of men's health (2023)
inhibiting BAX/BAK pathway in a rat model. TLR4 may play a key role in bonding NLRP3 inflammasome and BAX/BAK pathways. ESWT might be a promising approach for the treatment of CP/CPPS.
Keyphrases
- nlrp inflammasome
- chronic pain
- induced apoptosis
- toll like receptor
- inflammatory response
- signaling pathway
- oxidative stress
- pain management
- neuropathic pain
- stem cells
- immune response
- rectal cancer
- mouse model
- spinal cord
- mesenchymal stem cells
- bone marrow
- combination therapy
- spinal cord injury
- cell therapy
- replacement therapy
- nuclear factor