Neural stem/progenitor cells from olfactory neuroepithelium collected by nasal brushing as a cell model reflecting molecular and cellular dysfunctions in schizophrenia.
Carlo IdottaMario Angelo PaganoElena TibaldiMassimiliano CadamuroRoberto SaettiMarina SilvestriniGiorgio PigatoLeanza LuigiRoberta PeruzzoLeonardo MeneghettiStefano PiazzaPaolo MeneguzzoAngela FavaroLuigi GrassiTommaso ToffaninAnna Maria BrunatiPublished in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2024)
The ease and safety of sample collection as well as the differences observed between NS- and SZ-ONSPCs, may lay the groundwork for a new approach to obtain biological material from a large number of living individuals and gain a better understanding of the mechanisms underlying SZ pathophysiology.