Increased Risk of Invasive Aspergillosis in Immunocompromised Patients With Persistent SARS-CoV-2 Viral Shedding >8 Weeks, Retrospective Case-control Study.
Cléa MelenotteNathalie ChavarotAnne-Sophie L'HonneurSylvain BodardMorgane CheminantAdrien FlahaultYann NguyenMarianne BurgardEric DannaouiMarie-Elisabeth BougnouxPerrine ParizeClaire RouzaudAnne ScemlaEtienne CanouiEmmanuel LafontDamien VimpereJulien ZuberCaroline CharlierFelipe SuarezDany AnglicheauOlivier HermineFanny LanternierLuc MouthonOlivier LortholaryPublished in: Open forum infectious diseases (2024)
Vaccine coverage was protective against SARS-CoV-2 persistent viral shedding in immunocompromised patients. This new group of immunocompromised patients with SARS-CoV-2 persistent viral shedding is at risk of developing invasive aspergillosis and death and should therefore be systematically screened for this fungal infection for as long as the viral shedding persists.