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Association of parental divorce, discord, and polygenic risk with children's alcohol initiation and lifetime risk for alcohol use disorder.

Sally I-Chun KuoNathaniel S ThomasFazil AlievKathleen K BucholzDanielle M DickVivia V McCutcheonJacquelyn L MeyersGrace ChanChella KamarajanJohn R KramerVictor M HesselbrockMartin Henry PlaweckiBernice PorjeszJay TischfieldJessica E Salvatore
Published in: Alcoholism, clinical and experimental research (2023)
Children's genetic risk for alcohol problems modifies the impact of parental divorce/discord, consistent with an additive model of diathesis-stress interaction, with some differences across ancestry.
Keyphrases
  • young adults
  • mental health
  • dna methylation