High dose simultaneous integrated boost for node positive cervical cancer.
Iresha JayatilakebandaYat Man TsangPeter J HoskinPublished in: Radiation oncology (London, England) (2021)
Using a SIB, a total dose of 60 Gy in 25 fractions chemoradiation can be delivered to radiologically abnormal pelvic nodes with no increase in toxicity compared to node negative patients. The adverse impact of positive nodal status may be negated by high dose deposition using SIB, but larger prospective studies are required to confirm this observation.
Keyphrases
- high dose
- lymph node
- end stage renal disease
- low dose
- rectal cancer
- stem cell transplantation
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- oxidative stress
- sentinel lymph node
- squamous cell carcinoma
- radiation therapy
- neoadjuvant chemotherapy
- patient reported outcomes
- early stage
- oxide nanoparticles