A novel tumor suppressor CECR2 down regulation links glutamine metabolism contributes tumor growth in laryngeal squamous cell carcinoma.

Xiaoting WangChong XuShengming WangWeijun HuangYuenan LiuXiaoxu ZhangNiannian LiZhenfei GaoFan WangNan ZhangJian GuanHongliang YiFeng Liu

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2021)

We confirmed the Gln-αKG-CECR2 axis contributes to tumor growth in LSCC. This finding provided a potential therapeutic opportunity for the use of associated metabolites as a potential treatment for LSCC.

Keyphrases

squamous cell carcinoma
ms ms
risk assessment
radiation therapy
locally advanced
climate change
replacement therapy