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Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy.

Kurt D RistrophJie FengSimon A McManusYingyue ZhangKai GongHanu RamachandruniClaire E WhiteRobert K Prud'homme
Published in: Journal of translational medicine (2019)
The combined nanofabrication and drying process described herein, which utilizes two continuous unit operations that can be operated at scale, is an important step toward an industrially-relevant method of formulating the antimalarial OZ439 into a single-dose oral form with good stability against humidity and temperature.
Keyphrases
  • plasmodium falciparum
  • stem cells
  • bone marrow
  • smoking cessation