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Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia.

Sunny-Hei WongThomas N Y KwongTai-Cheong ChowArthur K C LukRudin Z W DaiGeicho NakatsuThomas Y T LamLin ZhangJustin C Y WuFrancis K L ChanSimon S M NgMartin C S WongSiew C NgWilliam K K WuJun YuJoseph J Y Sung
Published in: Gut (2016)
This study identified marker Fn as a valuable marker to improve diagnostic performance of FIT, providing a complementary role to detect lesions missed by FIT alone. This simple approach may improve the clinical utility of the current FIT, and takes one step further towards a non-invasive, potentially more accurate and affordable diagnosis of advanced colorectal neoplasia.
Keyphrases
  • high grade
  • ms ms
  • mass spectrometry
  • high resolution
  • liquid chromatography
  • tandem mass spectrometry
  • colorectal cancer screening
  • simultaneous determination
  • solid phase extraction