Predictors of 007 triphosphate concentrations in dried blood spots in persons with hepatitis C and active drug or alcohol use.
Kristina M BrooksJose R Castillo-MancillaMary MorrowSamantha MawhinneySarah E RowanDavid WylesJoshua BlumRyan HuntleyLana SalahArya TehraniLeah C JimmersonLaura RoonLane R BushmanPeter L AndersonJennifer J KiserPublished in: The Journal of antimicrobial chemotherapy (2022)
007-TP has an extended half-life in DBS and concentrations increased with adherence. Further research is needed to examine additional factors that affect 007-TP and the clinical utility of this measure.