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Intrinsic subtypes in Ethiopian breast cancer patient.

Zelalem DesalegnMeron YohannesMartin PorschKathrin StückrathEndale AnberberPablo SantosMarcus BauerAdamu AddissieYonas BekuretsionMathewos AssefaYasin WorkuLesley TaylorTamrat AbebeEva Johanna KantelhardtMartina Vetter
Published in: Breast cancer research and treatment (2022)
The distribution of the intrinsic subtypes confirms previous immunohistochemistry-based studies from Ethiopia showing potentially endocrine-sensitive tumors in more than half of the patients. Health workers in primary or secondary level health care facilities can be trained to offer endocrine therapy to improve breast cancer care. Additionally, the findings indicate that PAM50-based classification offers a robust method for the molecular classification of tumors in the Ethiopian context.
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