Arginyl-tRNA-protein transferase 1 contributes to governing optimal stability of the human immunodeficiency virus type 1 core.

Naoki KishimotoRyosuke OkanoAyano AkitaSatoshi MiuraAyaka IrieNobutoki TakamuneShogo Misumi

Published in: Retrovirology (2021)

These results indicate that ATE1 expression levels in HIV-1 producer cells contribute to the adequate formation of a stable HIV-1 core. These findings provide insights into a novel mechanism of HIV-1 uncoating and revealed ATE1 as a new host factor regulating HIV-1 replication.

Keyphrases

human immunodeficiency virus
antiretroviral therapy
hiv infected
hiv positive
hepatitis c virus
hiv aids
hiv testing
men who have sex with men
south africa
oxidative stress
binding protein
long non coding rna
cell death
signaling pathway