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Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models.

Birte Elisabeth DietzDave MuganQuoc Chi VuongIlona Obara
Published in: Neuromodulation : journal of the International Neuromodulation Society (2021)
This is the first evidence demonstrating the feasibility of recording ECAPs from the rat spinal cord, which may be more useful in determining parameters of SCS in preclinical SCS models than MTs. Thus, this approach may allow for the development of a novel model of SCS in rats with chronic pain that will translate better between animals and humans.
Keyphrases
  • spinal cord
  • chronic pain
  • spinal cord injury
  • neuropathic pain
  • cell therapy
  • oxidative stress
  • pain management
  • bone marrow