Study partner-reported decline identifies cognitive decline and dementia risk.

Rachel L NoshenyChengshi JinJohn NeuhausPhilip S InselRobert Scott MackinMichael W Weinernull null

Published in: Annals of clinical and translational neurology (2019)

SP-reported functional decline is an independent indicator of cognitive decline and dementia risk, even when accounting for cognitive screening, genetic risk, demographics, and self-report decline. The results provide a rationale for greater utilization of SP-reported functional decline to identify those at risk for dementia due to AD and other causes.

Keyphrases

cognitive decline
mild cognitive impairment
cognitive impairment
genome wide
dna methylation
copy number
hiv infected