Superiority of a Novel Mp1p Antigen Detection Enzyme Immunoassay Compared to Standard BACTEC Blood Culture in the Diagnosis of Talaromycosis.
Nguyen T M ThuJasper F W ChanVo Trieu LyHoa T NgoHa T A HienNguyen P H LanNguyen V V ChauJian-Piao CaiPatrick C Y WooJeremy N DayRogier van DoornGuy ThwaitesJohn PerfectKwok YuenThuy LePublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
The Mp1p EIA is highly specific and is superior in sensitivity and time to diagnosis compared to blood culture for the diagnosis of talaromycosis. Paired plasma and urine testing further increases sensitivity, introducing a new tool for rapid diagnosis, enabling early treatment and potentially reducing mortality.