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Stochastic Lanczos estimation of genomic variance components for linear mixed-effects models.

Richard BorderStephen Becker
Published in: BMC bioinformatics (2019)
Both the SLDF_REML and L_FOMC_REML algorithms outperform existing methods for REML estimation of variance components for LMM and are suitable for incorporation into existing GWAS LMM software implementations.
Keyphrases
  • machine learning
  • deep learning
  • gene expression