Long noncoding RNA polymorphisms influence susceptibility to endemic pemphigus foliaceus.

S C Lobo-AlvesD G AugustoW C S MagalhãesE Tarazona-SantosM F Lima-CostaM L BarretoB L HortaR C de AlmeidaMaria Luiza Petzl-Erler

Published in: The British journal of dermatology (2019)

We showed, for the first time, that variation in lncRNA genes may influence pemphigus pathogenesis. Our findings highlight the importance of lncRNA variation in autoimmune and possibly other complex diseases and suggest polymorphisms for functional validation.

Keyphrases

long noncoding rna
genome wide
long non coding rna
gene expression
dna methylation
transcription factor
bioinformatics analysis